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Especially regarding the central nervous system, the expression of GLP-1 receptors in reward-related regions, such as the hypothalamus, amygdala, nucleus accumbens, paraventricular nucleus, ventral tegmental area, locus coeruleus, and brain stem [21] may suggest a possible association between reward learning and symptoms like anhedonia in diseases such as depression

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En el subgrupo de 1130 pacientes con alto riesgo renal (TFGe 33.9 mg/dl], reduccin sostenida de la TFGe 30% o necesidad de terapia de reemplazo renal) fue 15 % menor en la rama dulaglutida (HR: 0.85

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When weight loss happens more gradually, the body tends to preserve more lean mass

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