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doi:10.1172/JCI0215595 149

Ventricular tachycardia (VT), though rare, is the most dangerous arrhythmia associated with GLP-1 use in patients with underlying structural heart disease

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Healthcare providers should engage in shared decision-making with patients, discussing the potential benefits and risks of Semaglutide therapy and addressing any concerns or preferences

Similarly, a recent systematic review and meta-analysis including 27 randomized controlled trials (RCTs) found no association between GLP-1 RAs and increased incidence of suicidal ideation or suicide [13]

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