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The GI effects of GLP-1 drugs are actually part of their mechanism of action, not just unpleasant side effects

One benefit of GLP-1 receptor agonists is that they do not cause hypoglycemia when combined with metformin or thiazolidinediones, but the dose of concomitant sulphonylurea or insulin may have to be decreased to reduce the risk of hypoglycemic episodes

For women experiencing decreased desire while their partner experience is unchanged, scheduled intimacy, while it sounds unromantic, can actually help

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doi: 10.3390/ijms23073587, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 5