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Mild deficiency causes fatigue, brain fog, and mood changes

And eating too quickly or in too-large portions overwhelms a digestive system that is already operating at a slower pace due to the medication delayed gastric emptying effect

The primary risk factors include: Chronic constipation and straining during bowel movements Prolonged sitting on the toilet Diarrhoea (less commonly, but repeated episodes can contribute) Increased intra-abdominal pressure Given that Wegovy causes constipation in approximately 24% of users, patients who develop this side effect may experience harder stools and increased straining during defecation

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An endocrinologist explains the off-label practice of microdosing weight-loss drugs, how it works, and the potential health risks

At the same time, the clinical benefits of GLP-1s are compelling: beyond significant weight loss for many patients, semaglutide has demonstrated cardiovascular risk reductionbenefits that make outright exclusions a blunt instrument