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OXALIPLATIN INDUCES COLD AND MECHANICAL ALLODYNIA IN A SEX-DEPENDENT MANNER AND ALTERS MECHANOSENSITIVITY OF MOUSE SOMATOSENSORY NEURONS

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Oxidation of the tryptophan 32 residue of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity triggers the non-amyloid aggregation of the enzyme

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A general range for HbA1c levels is: People without diabetes have an HBA1c of less than 40mmol/mol Target levels for most people with diabetes is 50 55 mmol/mol