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[DOI] [PubMed] [Google Scholar] 24.Wang F, Yu G, Liu SY, et al

In parallel, downregulation of PGC-1 and inhibition of the NRF1/TFAM pathway reduce mitochondrial DNA (mtDNA) copy number and impair biogenesis, limiting the replenishment of damaged mitochondria ( 6.2 Endoplasmic reticulum The endoplasmic reticulum (ER) is a highly specialized organelle in eukaryotic cells that performs essential physiological functions, including lipid metabolism, calcium homeostasis, and the folding and maturation of secretory and membrane proteins (Wang et al., 2018)

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J Assoc Nurses AIDS Care 2010;21:1624